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Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum.
Chemical and Pharmaceutical Bulletin · 1986 · Vol. 34(7) · pp. 3025–3028
Aiko Morigiwa✉(Asahi Breweries (Japan))Katsuaki Kitabatake(Central Research Laboratories (United Kingdom))Yoshinori Fujimoto(Asahi Breweries (Japan))Nobuo Ikekawa(Asahi Breweries (Japan))
Abstract
The 70% MeOH extract of Ganoderma lucidum had an inhibitory effect on angiotensin converting enzyme activity, and from this extract, five new triterpenes, named ganoderal A, ganoderols A and B, and ganoderic acids K and S, were isolated. Their structures were determined on the basis of spectral evidence.
Fungal Biology and ApplicationsMedicinal plant effects and applicationsChemistryTerpenePolyporaceaeEnzymeInhibitory postsynaptic potentialGanodermaAngiotensin-converting enzymeGanoderma lucidumTriterpeneStereochemistry
MeSH terms
Angiotensin-Converting Enzyme InhibitorsAnimalsBasidiomycotaPolyporaceaeSwineTriterpenes
Citations
219
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2.84
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