articleTop 1% cited
Chemistry with [<sup>18</sup>F]Fluoride Ion
European Journal of Organic Chemistry · 2008 · Vol. 2008(17) · pp. 2853–2873
Lisheng Cai(National Institute of Mental Health)Shuiyu Lu(National Institutes of Health)Victor W. Pike✉(National Institute of Mental Health)
Abstract
Abstract The success of molecular imaging with positron‐emission tomography (PET) depends on the availability of selective molecular probes labeled with positron‐emitters, such asfluorine‐18 ( t 1/2 = 109.7 min). No‐carrier‐added (NCA) [ 18 F]fluoride ion ( 18 F – ) is the primary reagent for the preparation of 18 F‐labeled tracers in high specific activity. In this microreview, we survey current and advancing radiochemical methods and technologies for the use of NCA [ 18 F]fluoride ion in the preparation of 18 F‐labeled radiotracers for applications with PET. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and ApplicationsFluorine in Organic ChemistryChemistryFluorideRadiochemistryReagentIonPositron emission tomographyPet imagingNuclear chemistryInorganic chemistryPhysical chemistry
Funding
- National Institutes of Health
- National Institute of Mental Health
Citations
463
FWCI
30.67
field-weighted impact
References
159
Percentile
100%
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Citations per year
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