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Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
British Journal of Cancer · 2013 · Vol. 108(4) · pp. 914–923
Abstract
Tumour-infiltrating CD4(+)T(high)/CD8(+)T(high)/%Treg(low) and %M1(high)/M2(low) are independent prognosticators useful for evaluating the immune microenvironment of PDC.
Immune cells in cancerCancer Immunotherapy and BiomarkersPancreatic and Hepatic Oncology ResearchFOXP3Immune systemCD8CD68Pancreatic cancerTumor microenvironmentCD163Tumor-infiltrating lymphocytesBiologyImmunology
MeSH terms
FemaleHumansMacrophagesMaleMiddle AgedPancreatic NeoplasmsPrognosisCD4-Positive T-LymphocytesSurvival AnalysisLymphocytes, Tumor-InfiltratingDisease-Free SurvivalT-Lymphocytes, RegulatoryTumor Microenvironment
Funding
- Pancreas Research Foundation of Japan
- Princess Takamatsu Cancer Research Fund
Citations
846
FWCI
17.62
field-weighted impact
References
34
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100%
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Citations per year
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