articleTop 10% cited
Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production
Bioorganic & Medicinal Chemistry Letters · 1999 · Vol. 9(11) · pp. 1625–1630
George W. Muller✉(Bristol-Myers Squibb (Switzerland))Roger Chen(Bristol-Myers Squibb (Switzerland))Shaei‐Yun Huang(Bristol-Myers Squibb (Switzerland))Laura G. Corral(Bristol-Myers Squibb (Switzerland))Lu Min Wong(Bristol-Myers Squibb (Switzerland))Rebecca T. Patterson(Bristol-Myers Squibb (Switzerland))Yuxi Chen(Rockefeller University)Gilla Kaplan(Rockefeller University)David Stirling(Bristol-Myers Squibb (Switzerland))
Multiple Myeloma Research and TreatmentsPhosphodiesterase function and regulationProtein Kinase Regulation and GTPase SignalingThalidomideChemistryTumor necrosis factor alphaPeripheral blood mononuclear cellEnzyme inhibitorPharmacologyChemical synthesisAmino acidStereochemistryIn vitro
MeSH terms
BloodHumansModels, ChemicalStructure-Activity RelationshipThalidomideTumor Necrosis Factor-alphaInhibitory Concentration 50U937 Cells
Citations
338
FWCI
2.86
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15
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References
Thalidomide in the treatment of lepra reactions
Clinical Pharmacology & Therapeutics · 1965 · 532 citations
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