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DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

Cancer Letters · 2012 · Vol. 332(2) · pp. 237–248
Wynand P. RoosBernd Kaina
DNA Repair MechanismsCancer-related Molecular PathwaysCell death mechanisms and regulationDNA damageDNA repairBiologyCell biologyApoptosisDNAProgrammed cell deathAP siteCancer researchSurvivin

MeSH terms

SurvivinAnimalsAntineoplastic AgentsCell CycleDNADNA DamageDNA RepairGuanineHumansNeoplasmsPhosphorylationRadiation, IonizingSignal TransductionNF-kappa BCell Death

Funding

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz
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References
DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139
Journal of Biological Chemistry · 1998 · 5,347 citations
Relevance of nitrosamines to human cancer
Carcinogenesis · 1984 · 493 citations
Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle
Molecular and Cellular Biology · 2003 · 1,165 citations
Induction of NF-κB by the Akt/PKB kinase
Current Biology · 1999 · 852 citations
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
Annual Review of Immunology · 2000 · 4,725 citations
Mechanism of Eukaryotic Homologous Recombination
Annual Review of Biochemistry · 2008 · 1,652 citations
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