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Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

Radiotherapy and Oncology · 1999 · Vol. 53(2) · pp. 113–117

David M. Brizel✉(Duke Medical Center)Richard K. Dodge(Duke Medical Center)Robert Clough(Duke Medical Center)Mark W. Dewhirst(Duke Medical Center)

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Head and Neck Cancer Studies Head and Neck Surgical Oncology Ear and Head TumorsMedicineRadiation therapyPrimary tumorHead and neck cancerCancerNeck dissectionTumor hypoxiaLymph nodeAnemiaOxygenation

MeSH terms

AnemiaCarcinoma, Squamous CellHumansLymphatic MetastasisNeoplasm Recurrence, LocalOtorhinolaryngologic NeoplasmsOxygenPolarographySurvival RateDisease-Free Survival

Citations

545

FWCI

20.83

field-weighted impact

References

21

Percentile

100%

vs. same field & year

Citations per year

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References

Oxygenation predicts radiation response and survival in patients with cervix cancer

Radiotherapy and Oncology · 1998 · 601 citations

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

Radiotherapy and Oncology · 1993 · 821 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

British Journal of Cancer · 1977 · 8,398 citations

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

Radiotherapy and Oncology · 1996 · 923 citations

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

International Journal of Radiation Oncology*Biology*Physics · 1997 · 1,066 citations

Regression Models and Life-Tables

Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1972 · 38,926 citations

Nonparametric Estimation from Incomplete Observations

Journal of the American Statistical Association · 1958 · 38,793 citations

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