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Ionic mechanisms of electrical remodeling in human atrial fibrillation
Cardiovascular Research · 1999 · Vol. 44(1) · pp. 121–131
Ralph Bosch✉(University of Tübingen)
Abstract
AF in humans leads to important changes in atrial potassium and calcium currents that likely contribute to the decrease in APD and APD rate adaptation. These changes contribute to electrical remodeling in AF and are therefore important factors for the perpetuation of the arrhythmia.
Cardiac electrophysiology and arrhythmiasIon channel regulation and functionNeuroscience and Neural EngineeringInternal medicineAtrial fibrillationRepolarizationAtrial action potentialCardiologyCardiac transient outward potassium currentInward-rectifier potassium ion channelSinus rhythmAcetylcholineChemistry
MeSH terms
AcetylcholineAction PotentialsAgedAtrial FibrillationElectric StimulationFemaleHumansIon ChannelsMaleMiddle AgedCalcium ChannelsPotassium ChannelsSodium ChannelsPatch-Clamp TechniquesAtrial Appendage
Funding
- Bundesministerium für Bildung und Forschung
Citations
578
FWCI
11.94
field-weighted impact
References
39
Percentile
99%
vs. same field & year
Citations per year
Cited by
Electrical, contractile and structural remodeling during atrial fibrillation
Cardiovascular Research · 2002 · 1,438 citations
References
Atrial Fibrillation Begets Atrial Fibrillation
Circulation · 1995 · 3,473 citations
The natural history of atrial fibrillation: Incidence, risk factors, and prognosis in the manitoba follow-up study
The American Journal of Medicine · 1995 · 1,478 citations
Epidemiologic assessment of chronic atrial fibrillation and risk of stroke
Neurology · 1978 · 1,541 citations
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