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The distribution of fitness effects of new mutations

Nature Reviews Genetics · 2007 · Vol. 8(8) · pp. 610–618
Adam Eyre‐WalkerPeter D. Keightley
Evolution and Genetic DynamicsChromosomal and Genetic VariationsGenomics and Phylogenetic StudiesBiologyGeneticsCoding regionMutationMutation AccumulationMutagenesisComputational biologyMutation rateEvolutionary biologyGene

MeSH terms

AnimalsDNAHumansModels, GeneticMutationMutagenesisEvolution, MolecularAmino Acid SubstitutionPolymorphism, Single Nucleotide

Funding

  • Biotechnology and Biological Sciences Research Council
Citations
1,604
FWCI
24.28
field-weighted impact
References
95
Percentile
100%
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Citations per year
References
On the allelic spectrum of human disease
Trends in Genetics · 2001 · 1,186 citations
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