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Clinical Treatment of Radiotherapy Tissue Damage by Lipoaspirate Transplant: A Healing Process Mediated by Adipose-Derived Adult Stem Cells

Plastic & Reconstructive Surgery · 2007 · Vol. 119(5) · pp. 1409–1422

Gino Rigotti✉(Politecnico di Milano)Alessandra Marchi(Ospedale Maggiore)Mirco Gali(Politecnico di Milano)G. Baroni(Politecnico di Milano)Donatella Benati(Politecnico di Milano)Mauro Krampera(Ospedale Maggiore)Annalisa Pasini(Politecnico di Milano)Andrea Sbarbati(Politecnico di Milano)

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Abstract

This surgical procedure is a low-invasive therapeutic approach for resolving the late side effects of radiotherapy. According to the proposed hypothesis of the ischemic nature of radiolesions, treatment with lipoaspirate transplantation is potentially extended to other forms of microangiopathies.

Mesenchymal stem cell research Tissue Engineering and Regenerative Medicine Reconstructive Surgery and Microvascular TechniquesMedicineStromal vascular fractionStem cellMesenchymal stem cellAdipose tissueTransplantationSurgeryStem-cell therapyWound healingStromal cell

MeSH terms

AdultAgedBreast NeoplasmsFemaleFollow-Up StudiesHumansMiddle AgedRadiation InjuriesRadiotherapyTime FactorsStem Cell TransplantationSubcutaneous FatAdult Stem Cells

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Concise Review: Adipose‐Derived Stem Cells as a Novel Tool for Future Regenerative Medicine