article Open AccessTop 1% cited
Structural basis for CRISPR RNA-guided DNA recognition by Cascade
Nature Structural & Molecular Biology · 2011 · Vol. 18(5) · pp. 529–536
Matthijs M. Jore✉(Wageningen University & Research)Magnus Lundgren(Imperial College London)Esther van Duijn(Utrecht University)Jelle B. Bultema(University of Groningen)Edze R. Westra(Wageningen University & Research)Sakharam Waghmare(University of Sheffield)Blake Wiedenheft(Howard Hughes Medical Institute)Ümit Pul(Heinrich Heine University Düsseldorf)Reinhild Wurm(Heinrich Heine University Düsseldorf)Rolf Wagner(Heinrich Heine University Düsseldorf)Marieke R. Beijer(Wageningen University & Research)Arjan Barendregt(Utrecht University)Kaihong Zhou(Lawrence Berkeley National Laboratory)Ambrosius P. Snijders(Imperial College London)Mark J. Dickman(University of Sheffield)Jennifer A. Doudna(Howard Hughes Medical Institute)Egbert J. Boekema(University of Groningen)Albert J. R. Heck(Netherlands Metabolomics Centre)John van der Oost(Wageningen University & Research)Stan J. J. Brouns(Wageningen University & Research)
CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniquesTrans-activating crRNACRISPRDNABiologyRNACas9PlasmidRibonucleoproteinBase pairPalindrome
MeSH terms
Base SequenceBinding SitesDNAEscherichia coliNucleic Acid ConformationRibonucleoproteinsRNA, BacterialStructure-Activity RelationshipProtein Structure, TertiaryEscherichia coli ProteinsRNA, Small Untranslated
Funding
- Howard Hughes Medical Institute
- Life Sciences Research Foundation
- Research Councils UK
- Deutsche Forschungsgemeinschaft
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Directorate for Biological Sciences
- Engineering and Physical Sciences Research Council
Citations
577
FWCI
23.56
field-weighted impact
References
52
Percentile
100%
vs. same field & year
Citations per year
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References
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Phage Response to CRISPR-Encoded Resistance in <i>Streptococcus thermophilus</i>
Journal of Bacteriology · 2007 · 1,239 citations
Short motif sequences determine the targets of the prokaryotic CRISPR defence system
Microbiology · 2009 · 1,550 citations
A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes
PLoS Computational Biology · 2005 · 979 citations
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
Microbiology · 2005 · 1,710 citations
Diversity, Activity, and Evolution of CRISPR Loci in <i>Streptococcus thermophilus</i>
Journal of Bacteriology · 2007 · 786 citations
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