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Epithelial-mesenchymal signalling regulating tooth morphogenesis

Journal of Cell Science · 2003 · Vol. 116(9) · pp. 1647–1648
Irma Thesleff

Abstract

Teeth develop as ectodermal appendages in vertebrate embryos, and their early development resembles morphologically as well as molecularly other organs such as hairs and glands. Interactions between the ectoderm and underlying mesenchyme constitute a central mechanism regulating the morphogenesis of

dental development and anomaliesOral and Maxillofacial PathologyCancer-related gene regulationBiologyMesenchymal stem cellCell biologyMorphogenesisSignallingGeneticsGene

MeSH terms

AnimalsEpitheliumFibroblast Growth FactorsHumansMesodermMice, Mutant StrainsModels, BiologicalOdontogenesisSignal TransductionTransforming Growth Factor betaBone Morphogenetic ProteinsMice
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Epithelial-mesenchymal signalling regulating tooth morphogenesis · Scinovex