articleTop 1% cited

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition

Biochemical Pharmacology · 1997 · Vol. 53(11) · pp. 1649–1657

Georgine AgulloLaurence Gamet‐Payrastre✉Stéphane Manenti(Inserm)Cécile Viala(Hôpital Purpan)Christian RémésyHugues Chap(Inserm)Bernard Payrastre(Inserm)

View via DOI Publisher page

Flavonoids in Medical Research Natural Antidiabetic Agents Studies Phytochemicals and Antioxidant ActivitiesBiochemistryTyrosine kinaseChemistryKinasePhosphatidylinositolProtein kinase CSignal transductionBiology

MeSH terms

Dose-Response Relationship, DrugFlavonoidsProtein Kinase CProtein-Tyrosine KinasesQuercetinStructure-Activity RelationshipPhosphotransferases (Alcohol Group Acceptor)Phosphatidylinositol 3-KinasesFlavonolsLuteolin

Citations

536

FWCI

13.45

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

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References

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Journal of Biological Chemistry · 1994 · 3,250 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Journal of Biological Chemistry · 1987 · 3,734 citations

Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

Archives of Internal Medicine · 1995 · 1,763 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Nature · 1970 · 251,243 citations

The flavonoids advances in research since 1986:

Phytochemistry · 1994 · 1,591 citations

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