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International consensus report on the investigation and management of primary immune thrombocytopenia

Blood · 2009 · Vol. 115(2) · pp. 168–186

Drew Provan✉Roberto Stasi(South West London and St George's Mental Health NHS Trust)Adrian C. NewlandVictor S. Blanchette(Hospital for Sick Children)Paula Bolton‐Maggs(Manchester Royal Infirmary)James B. BusselBeng H. Chong(St George Hospital)Douglas B. Cines(Hospital of the University of Pennsylvania)Terry Gernsheimer(Bloodworks Northwest)Bertrand Godeau(Assistance Publique – Hôpitaux de Paris)John D. Grainger(Royal Manchester Children's Hospital)Ian Greer(University of York)Beverley J. Hunt(Guy's and St Thomas' NHS Foundation Trust)Paul Imbach(University Children’s Hospital Basel)G. Lyons(St James's University Hospital)Robert McMillan(Scripps Research Institute)Francesco Rodeghiero(Ospedale San Bortolo)Miguel Á. Sanz(Hospital Universitari i Politècnic La Fe)Michael D. Tarantino(Bleeding & Clotting Disorders Institute)Shirley WatsonJoan YoungDavid J. Kuter(Massachusetts General Hospital)

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Abstract

Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010. A critical review was performed to identify all relevant articles published between 2009 and 2018. An expert panel screened, reviewed, and graded the studies and formulated the updated consensus recommendations based on the new data. The final document provides consensus recommendations on the diagnosis and management of ITP in adults, during pregnancy, and in children, as well as quality-of-life considerations.

Platelet Disorders and Treatments Blood groups and transfusion Blood properties and coagulationImmune thrombocytopeniaMedicineIntensive care medicineClinical trialConsensus conferenceMEDLINEPediatricsImmunologyPathologyInternal medicine