article Open AccessTop 10% cited
Near-Infrared Autofluorescence Imaging of the Fundus: Visualization of Ocular Melanin
Investigative Ophthalmology & Visual Science · 2006 · Vol. 47(8) · pp. 3556–3556
Claudia N. Keilhauer✉(Universitätsklinikum Würzburg)Franc ̧ois C. Delori(Harvard University)
Abstract
AF[787] originates from the RPE and to a varying degree from the choroid. Oxidized melanin, or compounds closely associated with melanin, contributes substantially to this AF, but other fluorophores cannot be excluded at this stage. Confocal AF[787] imaging may provide a new modality to visualize pathologic features of the RPE and the choroid, and, together with AF[488] imaging, offers a new tool to study biological changes associated with aging of the RPE and pathology.
Retinal Diseases and TreatmentsRetinal Development and DisordersGlaucoma and retinal disordersAutofluorescenceRetinal pigment epitheliumFundus (uterus)OphthalmoscopyOphthalmologyMelaninChoroidScanning laser ophthalmoscopyMedicineConfocal
MeSH terms
AdolescentAdultAgedChildChoroidFemaleFluorescenceFundus OculiHumansImage Processing, Computer-AssistedInfrared RaysMaleMelaninsMiddle AgedOphthalmoscopy
Citations
386
FWCI
8.86
field-weighted impact
References
52
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98%
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Citations per year
References
Histology of the Human Eye.
Archives of Ophthalmology · 1972 · 800 citations
Distribution of fundus autofluorescence with a scanning laser ophthalmoscope.
British Journal of Ophthalmology · 1995 · 520 citations
Human photoreceptor topography
The Journal of Comparative Neurology · 1990 · 2,726 citations
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