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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

The EMBO Journal · 1998 · Vol. 17(18) · pp. 5497–5508
Minoru TakataMasao S. SasakiEiichiro SonodaCiaran G. MorrisonMitsumasa HashimotoHiroshi UtsumiYuko Yamaguchi‐IwaiAkira ShinoharaShunichi Takeda
DNA Repair MechanismsCRISPR and Genetic EngineeringCarcinogens and Genotoxicity AssessmentKu70BiologyHomologous recombinationNon-homologous end joiningDNA repairKu80DNA repair protein XRCC4Cell biologyHomology directed repairGenetics

MeSH terms

Ku AutoantigenAmino Acid SequenceAnimalsB-LymphocytesCell LineChickensChromosome AberrationsCloning, MolecularDNA RepairDNA HelicasesDNA-Binding ProteinsGamma RaysInterphaseMolecular Sequence DataNuclear Proteins

Funding

  • Kindai University
  • University of Sussex
  • Universität Hamburg
  • Mochida Memorial Foundation for Medical and Pharmaceutical Research
  • University of California, San Francisco
  • Bayer Yakuhin
  • Japan Society for the Promotion of Science
  • Lawrence Livermore National Laboratory
Citations
1,210
FWCI
14.17
field-weighted impact
References
83
Percentile
99%
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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells · Scinovex