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The Mechanisms of Action of NSAIDs in Analgesia

Drugs · 1996 · Vol. 52(Supplement 5) · pp. 13–23
J. N. Cashman
Inflammatory mediators and NSAID effectsEicosanoids and Hypertension PharmacologyPain Mechanisms and TreatmentsMechanism of actionPharmacologyAnalgesicProstaglandinCyclooxygenaseMedicineReceptorEndogenyProstaglandin E2Enzyme

MeSH terms

AnalgesiaAnimalsAnti-Inflammatory Agents, Non-SteroidalHumansInflammationLipoxygenasePainProstaglandin-Endoperoxide SynthasesN-MethylaspartateArachidonic AcidLipoxygenase InhibitorsCyclooxygenase InhibitorsRats
Citations
491
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References
87
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Cited by
Cyclooxygenase in biology and disease
The FASEB Journal · 1998 · 2,501 citations
References
Inflammatory mediators of pain
British Journal of Anaesthesia · 1995 · 597 citations
Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.
Journal of Pharmacology and Experimental Therapeutics · 1992 · 653 citations
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The Mechanisms of Action of NSAIDs in Analgesia · Scinovex