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Role of Particle Size in Phagocytosis of Polymeric Microspheres

Pharmaceutical Research · 2008 · Vol. 25(8) · pp. 1815–1821
Julie A. ChampionAmanda H. WalkerSamir Mitragotri
Phagocytosis and Immune RegulationNanoparticle-Based Drug DeliveryInhalation and Respiratory Drug DeliveryMicrospherePhagocytosisParticle sizePharmaceutical technologyDosage formMicroparticleChemistryParticle (ecology)NanotechnologyMaterials science

MeSH terms

AlgorithmsAnimalsCell LineFlow CytometryMicroscopy, Electron, ScanningMicrospheresParticle SizePhagocytosisPolymersMacrophages, AlveolarMicroscopy, VideoRats

Funding

  • National Science Foundation
  • Materials Research Science and Engineering Center, Harvard University
Citations
874
FWCI
7.08
field-weighted impact
References
41
Percentile
98%
vs. same field & year
Citations per year
References
Biodegradable microspheres for protein delivery
Journal of Controlled Release · 2003 · 800 citations
Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
International Journal of Pharmaceutics · 2005 · 3,492 citations
MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES
Annual Review of Immunology · 1999 · 2,832 citations
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