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Naive pluripotency is associated with global DNA hypomethylation

Nature Structural & Molecular Biology · 2013 · Vol. 20(3) · pp. 311–316

Harry G. Leitch✉(Wellcome/MRC Cambridge Stem Cell Institute)Kirsten R. McEwen(Imperial College London)Aleksandra Turp(Medical Research Council)Vesela Encheva(Imperial College London)Tom Carroll(Medical Research Council)Nils Grabole(University of Cambridge)W Mansfield(Medical Research Council)Buhe Nashun(Medical Research Council)Jaysen Knezovich(University of Cambridge)Austin Smith(Wellcome/MRC Cambridge Stem Cell Institute)M. Azim Surani(Wellcome/Cancer Research UK Gurdon Institute)Petra Hájková(Medical Research Council)

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Epigenetics and DNA Methylation Pluripotent Stem Cells Research Renal and related cancersEpiblastBiologyDNA methylationEmbryonic stem cellGerm layerInduced pluripotent stem cellCell biologyEpigeneticsDNA demethylationDNMT3B

MeSH terms

Glycogen Synthase Kinase 3 betaDNA Methyltransferase 3ADNA Methyltransferase 3BAnimalsBenzamidesCell DifferentiationCells, CulturedDiphenylamineDNA (Cytosine-5-)-MethyltransferasesDNA-Binding ProteinsEnzyme InhibitorsGerm CellsGerm LayersMice, Inbred C57BLPyridines