article Open AccessTop 10% cited

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

Metabolism · 2008 · Vol. 57(8) · pp. 1071–1077

Naoto Nagata(Kanazawa University)Toshinari Takamura✉(Kanazawa University)Hitoshi Ando(Kanazawa University)Seiji Nakamura(Kanazawa University)Seiichiro Kurita(Kanazawa University)Hirofumi Misu(Kanazawa University)Tsuguhito Ota(Kanazawa University)Masayoshi Yokoyama(Kanazawa University)Masao Honda(Kanazawa University)Ken‐ichi Miyamoto(Kanazawa University)Shuichi Kaneko(Kanazawa University)

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Peroxisome Proliferator-Activated Receptors Adipose Tissue and Metabolism Adipokines, Inflammation, and Metabolic DiseasesInsulin resistanceEndocrinologyInternal medicineAdipose tissueNicotinamide adenine dinucleotide phosphateOxidative stressPeroxisomeBiologyInsulinInsulin receptor

MeSH terms

Adipose TissueAnimalsBlood GlucoseBody WeightDietary FatsGlucose Tolerance TestInsulinInsulin ResistanceLiverMaleMice, Inbred C57BLObesityRNA, MessengerUp-RegulationReactive Oxygen Species

Citations

536

FWCI

10.07

field-weighted impact

References

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99%

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References

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.

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