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The prevalence of BRCA1 mutations among young women with triple-negative breast cancer

BMC Cancer · 2009 · Vol. 9(1) · pp. 86–86
S. R. YoungRobert PilarskiTalia DonenbergCharles L. ShapiroLyn S. HammondJudith MillerKaren BrooksStephanie A. CohenBeverly TenenholzDamini DeSaiInuk ZandvakiliRobert E. RoyerSong LiSteven A. Narod

Abstract

Women with early-onset triple-negative breast cancer are candidates for genetic testing for BRCA1, even in the absence of a family history of breast or ovarian cancer.

BRCA gene mutations in cancerCancer Genomics and DiagnosticsDNA Repair MechanismsTriple-negative breast cancerSurgical oncologyMedicineBreast cancerOncologyInternal medicineCancer

MeSH terms

AdultBreast NeoplasmsDNA Mutational AnalysisFemaleGene FrequencyGenetic TestingHumansMutationReceptors, EstrogenReceptors, ProgesteroneErb-b2 Receptor Tyrosine KinasesReceptor, ErbB-2BRCA1 ProteinYoung Adult

Funding

  • Ohio State University
Citations
273
FWCI
14.01
field-weighted impact
References
24
Percentile
99%
vs. same field & year
Citations per year
References
Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence
Clinical Cancer Research · 2007 · 5,037 citations
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