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Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis

BMJ · 2007 · Vol. 335(7627) · pp. 974–974
Leanne BellamyJuan-Pablo CasasAroon D. HingoraniDavid Williams

Abstract

A history of pre-eclampsia should be considered when evaluating risk of cardiovascular disease in women. This association might reflect a common cause for pre-eclampsia and cardiovascular disease, or an effect of pre-eclampsia on disease development, or both. No association was found between pre-eclampsia and future cancer.

Pregnancy and preeclampsia studiesBirth, Development, and HealthCancer Risks and FactorsMedicineEclampsiaDiseaseStroke (engine)Relative riskCohort studyCancerMeta-analysisConfidence intervalProspective cohort study

MeSH terms

Age FactorsCardiovascular DiseasesCause of DeathFemaleFollow-Up StudiesHumansNeoplasmsPre-EclampsiaPregnancyRisk Factors

Funding

  • NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
  • National Institute for Health and Care Research
  • British Heart Foundation
  • University College London Hospitals NHS Foundation Trust
Citations
2,512
FWCI
58.43
field-weighted impact
References
38
Percentile
100%
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Citations per year
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References
Preeclampsia: An endothelial cell disorder
American Journal of Obstetrics and Gynecology · 1989 · 1,863 citations
Preeclampsia: An excessive maternal inflammatory response to pregnancy
American Journal of Obstetrics and Gynecology · 1999 · 1,853 citations
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