article Open AccessTop 1% cited
Disordered Microbial Communities in Asthmatic Airways
PLoS ONE · 2010 · Vol. 5(1) · pp. e8578–e8578
Markus Hilty(Lung Institute)Conor M. Burke(Connolly Hospital Blanchardstown)Helder Pedro(Instituto Gulbenkian de Ciência)Paúl Cárdenas(Imperial College London)Andrew Bush(Imperial College London)Cara Bossley(Imperial College London)Jane C. Davies(Lung Institute)Aaron Ervine(Connolly Hospital Blanchardstown)Len W. Poulter(Connolly Hospital Blanchardstown)Lior Pachter(University of California, Berkeley)Miriam F. Moffatt(Imperial College London)William Cookson✉(Imperial College London)
Abstract
The results show the bronchial tree to contain a characteristic microbiota, and suggest that this microbiota is disturbed in asthmatic airways.
Gut microbiota and healthProbiotics and Fermented FoodsPediatric health and respiratory diseasesAsthmaPrevotellaProteobacteriaBacteroidetesHaemophilusAirwayMedicineCOPDImmunologyMicrobiology
MeSH terms
AdolescentAdultAsthmaBacteriaBronchoalveolar Lavage FluidChildFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SSpecies SpecificityCase-Control StudiesYoung Adult
Funding
- Wellcome Trust
- European Commission
Citations
1,810
FWCI
33.81
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
Cited by
Proteobacteria: A Common Factor in Human Diseases
BioMed Research International · 2017 · 1,219 citations
The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease
PLoS Pathogens · 2015 · 539 citations
Role of the Microbiota in Immunity and Inflammation
Cell · 2014 · 5,168 citations
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
European Respiratory Journal · 2013 · 3,864 citations
Obesity and asthma
Journal of Allergy and Clinical Immunology · 2018 · 879 citations
Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age
Journal of Allergy and Clinical Immunology · 2011 · 780 citations
Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract
American Journal of Respiratory and Critical Care Medicine · 2011 · 1,119 citations
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
Nature Medicine · 2014 · 2,722 citations
References
Community study of role of viral infections in exacerbations of asthma in 9-11 year old children
BMJ · 1995 · 1,998 citations
Bacterial Diversity in Human Subgingival Plaque
Journal of Bacteriology · 2001 · 2,007 citations
Defining the Normal Bacterial Flora of the Oral Cavity
Journal of Clinical Microbiology · 2005 · 3,070 citations
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Proceedings of the National Academy of Sciences · 2007 · 4,550 citations
Introducing DOTUR, a Computer Program for Defining Operational Taxonomic Units and Estimating Species Richness
Applied and Environmental Microbiology · 2005 · 2,505 citations
UniFrac – An online tool for comparing microbial community diversity in a phylogenetic context
BMC Bioinformatics · 2006 · 1,461 citations
Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness
The Journal of Infectious Diseases · 2008 · 1,632 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.