articleTop 1% cited
Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen
Journal of Molecular Biology · 1997 · Vol. 267(3) · pp. 727–748
Gareth Jones✉(University of Sheffield)Peter Willett(University of Sheffield)Robert C. Glen(Wellcome Trust)Andrew R. Leach(Wellcome Trust)Robin Taylor(Cambridge Crystallographic Data Centre)
Computational Drug Discovery MethodsProtein Degradation and InhibitorsClick Chemistry and ApplicationsDocking (animal)Protein–ligand dockingSearching the conformational space for dockingLigand (biochemistry)DOCKComputer scienceFlexibility (engineering)AlgorithmMacromoleculeMolecular dynamics
MeSH terms
AlgorithmsBinding SitesComputer SimulationHumansLigandsModels, GeneticModels, MolecularNADPProtein BindingProtein ConformationProteinsTetrahydrofolate DehydrogenaseCrystallography, X-Ray
Citations
6,621
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89
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