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The epidemiology and natural history of Crohn’s disease in population‐based patient cohorts from North America: a systematic review

Alimentary Pharmacology & Therapeutics · 2002 · Vol. 16(1) · pp. 51–60

Edward V. Loftus✉(Mayo Clinic in Arizona)Philip Schoenfeld(University of Michigan–Ann Arbor)William J. Sandborn(Mayo Clinic in Arizona)

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Abstract

Between 400,000 and 600,000 patients in North America have Crohn's disease, and the natural history is marked by frequent exacerbations requiring treatment with corticosteroids, 5-aminosalicylate products and surgery.

Inflammatory Bowel Disease Microscopic Colitis Autoimmune and Inflammatory DisordersMedicineNatural historyEpidemiologyIncidence (geometry)Crohn's diseaseDiseasePopulationPediatricsInternal medicineSurgery

MeSH terms

AdolescentAdrenal Cortex HormonesAdultAge FactorsAgedChildChild, PreschoolChronic DiseaseCrohn DiseaseFemaleHumansInfantInfant, NewbornMaleMiddle Aged