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Regularized gene selection in cancer microarray meta-analysis

BMC Bioinformatics · 2009 · Vol. 10(1) · pp. 1–1
Shuangge MaJian Huang

Abstract

The MTGDR provides an effective way of analyzing multiple cancer microarray studies and selecting reliable cancer-associated genes.

Gene expression and cancer classificationBioinformatics and Genomic NetworksMolecular Biology Techniques and ApplicationsDNA microarrayMicroarray analysis techniquesMeta-analysisSelection (genetic algorithm)Computational biologyPancreatic cancerCancerGene selectionMicroarrayComputer science

MeSH terms

AlgorithmsBayes TheoremComputer SimulationFemaleHumansLiver NeoplasmsMaleNeoplasmsPancreatic NeoplasmsBiomarkers, TumorGene Expression Regulation, NeoplasticCluster AnalysisComputational BiologyOligonucleotide Array Sequence AnalysisGene Expression Profiling

Funding

  • Yale University
  • Georgia Clinical and Translational Science Alliance
  • National Institutes of Health
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Regularized gene selection in cancer microarray meta-analysis · Scinovex