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Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication

Biochimica et Biophysica Acta (BBA) - General Subjects · 1998 · Vol. 1425(3) · pp. 527–533

Stephan Pflugmacher✉(Leibniz Institute of Freshwater Ecology and Inland Fisheries)Claudia Wiegand(Leibniz Institute of Freshwater Ecology and Inland Fisheries)Axel Oberemm(Leibniz Institute of Freshwater Ecology and Inland Fisheries)Kenneth A. Beattie(University of Dundee)Eberhard KrauseGeoffrey A. Codd(University of Dundee)Christian E. W. Steinberg(Leibniz Institute of Freshwater Ecology and Inland Fisheries)

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Aquatic Ecosystems and Phytoplankton Dynamics Glutathione Transferases and Polymorphisms Biocrusts and Microbial EcologyMicrocystinGlutathioneBiologyCyanobacteriaMicrocystin-LRAquatic ecosystemDreissenaHepatotoxinEnvironmental chemistryChemistry

MeSH terms

CyanobacteriaAnimalsBacterial ToxinsBiotransformationChromatography, High Pressure LiquidDinitrochlorobenzeneFishesGlutathioneGlutathione TransferaseMarine ToxinsPeptides, CyclicMass SpectrometryWater MicrobiologyMicrocystins

Citations

552

FWCI

4.70

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95%

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Effects of microcystins on fish