article Open AccessTop 1% cited
Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells
Immunity · 2010 · Vol. 32(6) · pp. 815–827
Hsin-Jung Wu(Joslin Diabetes Center)Ivaylo I. Ivanov(New York University)Jaime Darce(Harvard University)Kimie Hattori(Harvard University)Tatsuichiro Shima(Yakult Central Institute)Yoshinori Umesaki(Yakult Central Institute)Dan R. Littman(Howard Hughes Medical Institute)Christophe Benoıst✉(Harvard University)Diane Mathis✉(Harvard University)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesLamina propriaGerminal centerImmunologyAutoantibodyBiologyArthritisAutoimmune diseaseAutoimmunityInterleukin 17Population
MeSH terms
AnimalsArthritis, ExperimentalArthritis, RheumatoidBacteriaCell SeparationEnzyme-Linked Immunosorbent AssayFlow CytometryT-Lymphocytes, Helper-InducerIntestinesReverse Transcriptase Polymerase Chain ReactionInterleukin-17Mice
Funding
- National Institutes of Health
- School of Medicine, New York University
Citations
1,537
FWCI
35.07
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature Reviews Microbiology · 2008 · 1,690 citations
Hay fever, hygiene, and household size.
BMJ · 1989 · 5,032 citations
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
Cell · 2009 · 4,441 citations
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
Cell · 2006 · 5,064 citations
Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense
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