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The Use of Sieves to Stabilize Images Produced with the EM Algorithm for Emission Tomography

IEEE Transactions on Nuclear Science · 1985 · Vol. 32(5) · pp. 3864–3872
Donald L. SnyderMichael I. Miller

Abstract

Images produced in emission tomography with the expectation-maximization (EM) algorithm have been observed to become more 'noisy' as the algorithm converges towards the maximum-likelihood estimate. We argue in this paper that there is an instability which is fundamental to maximum-likelihood estimation as it is usually applied and, therefore, is not a result of using the EM algorithm, which is but one numerical implementation for producing maximum-likelihood estimates. We show how Grenader's method of sieves can be used with the EM algorithm to remove the instability and thereby decrease the 'noise' artifact introduced into the images with little or no increase in computational complexity.

Medical Imaging Techniques and ApplicationsAdvanced X-ray and CT ImagingAdvanced MRI Techniques and ApplicationsExpectation–maximization algorithmAlgorithmMaximum likelihoodNoise (video)Maximum likelihood sequence estimationArtifact (error)TomographyComputer scienceInstabilityEstimation theory

Funding

  • University of Washington
  • Johns Hopkins University
Citations
271
FWCI
3.52
field-weighted impact
References
22
Percentile
93%
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Citations per year
Cited by
Bayesian reconstructions from emission tomography data using a modified EM algorithm
IEEE Transactions on Medical Imaging · 1990 · 1,231 citations
References
Maximum Likelihood from Incomplete Data Via the <i>EM</i> Algorithm
Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1977 · 49,286 citations
Maximum Likelihood Reconstruction for Emission Tomography
IEEE Transactions on Medical Imaging · 1982 · 4,359 citations
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