articleTop 1% cited

Hypotensive Resuscitation during Active Hemorrhage: Impact on In-Hospital Mortality

The Journal of Trauma: Injury, Infection, and Critical Care · 2002 · Vol. 52(6) · pp. 1141–1146

Richard P. Dutton✉(University of Maryland, Baltimore)Colin F. MackenzieThomas M. Scalea

Abstract

Titration of initial fluid therapy to a lower than normal SBP during active hemorrhage did not affect mortality in this study. Reasons for the decreased overall mortality and the lack of differentiation between groups likely include improvements in diagnostic and therapeutic technology, the heterogeneous nature of human traumatic injuries, and the imprecision of SBP as a marker for tissue oxygen delivery.

Trauma, Hemostasis, Coagulopathy, Resuscitation Trauma and Emergency Care Studies Cardiac Arrest and ResuscitationMedicineResuscitationAnesthesiaShock (circulatory)HemostasisBlood pressureInjury Severity ScoreClinical endpointMean arterial pressureRandomized controlled trial

MeSH terms

AdultBlood PressureFemaleFluid TherapyHumansHypotensionLength of StayMaleResuscitationShock, HemorrhagicWounds, NonpenetratingInjury Severity ScoreSurvival RateHospital Mortality

Citations

585

FWCI

13.43

field-weighted impact

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99%

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Cited by

Advanced Trauma Life Support, 8th Edition, The Evidence for Change