article Open AccessTop 1% cited
Feasibility of Onchocerciasis Elimination with Ivermectin Treatment in Endemic Foci in Africa: First Evidence from Studies in Mali and Senegal
PLoS neglected tropical diseases · 2009 · Vol. 3(7) · pp. e497–e497
Lamine DiawaraMamadou O. TraoréAlioune BadjiYiriba BissanKonimba DoumbiaSoula F. GoitaLassana Konaté(Cheikh Anta Diop University)Kalifa MounkoroMoussa D. SarrAmadou F. SeckLaurent ToéSeyni TouréeJ Remme✉(ORT France)
Abstract
This study has provided the first empirical evidence that elimination of onchocerciasis with ivermectin treatment is feasible in some endemic foci in Africa. Although further studies are needed to determine to what extent these findings can be extrapolated to other endemic areas in Africa, the principle of elimination has been established. The African Programme for Onchocerciasis Control has adopted an additional objective to assess progress towards elimination endpoints in all onchocerciasis control projects and to guide countries on cessation of treatment where feasible.
Parasitic Diseases Research and TreatmentParasite Biology and Host InteractionsParasites and Host InteractionsIvermectinOnchocerciasisOnchocerca volvulusTransmission (telecommunications)InfectivityVector (molecular biology)Veterinary medicineBiologyEpidemiologyMedicine
MeSH terms
AdultAnimalsFemaleFilaricidesHumansIvermectinLongitudinal StudiesMaleMaliOnchocerciasisSenegalSimuliidaePrevalencePolymerase Chain ReactionOnchocerca volvulus
Funding
- Bill and Melinda Gates Foundation
- UNICEF
Citations
475
FWCI
20.03
field-weighted impact
References
55
Percentile
100%
vs. same field & year
Citations per year
Cited by
A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases
PLoS neglected tropical diseases · 2012 · 336 citations
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