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A COMPARISON OF TACROLIMUS (FK506) AND CYCLOSPORINE FOR IMMUNOSUPPRESSION AFTER CADAVERIC RENAL TRANSPLANTATION1
Transplantation · 1997 · Vol. 63(7) · pp. 977–983
Abstract
Tacrolimus is more effective than cyclosporine in preventing acute rejection in cadaveric renal allograft recipients, and significantly reduces the use of antilymphocyte antibody preparations. Tacrolimus was associated with a higher incidence of neurologic events, which were rarely treatment limiting, and with posttransplant diabetes mellitus, which was reversible in some patients.
Renal Transplantation Outcomes and TreatmentsOrgan Transplantation Techniques and OutcomesNeurological Complications and SyndromesTacrolimusMedicineImmunosuppressionTransplantationCiclosporinGastroenterologyIncidence (geometry)KidneyKidney transplantationUrology
MeSH terms
Acute DiseaseAdultAntilymphocyte SerumCadaverCause of DeathClinical ProtocolsCreatinineDiabetes MellitusFemaleGraft RejectionHumansImmunosuppressive AgentsInsulinMaleRegression Analysis
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References
MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION IN PRIMARY CADAVERIC RENAL ALLOGRAFT RECIPIENTS
Transplantation · 1995 · 1,382 citations
International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology
Kidney International · 1993 · 1,458 citations
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