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Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents?

Bioorganic & Medicinal Chemistry · 2001 · Vol. 9(3) · pp. 703–714
Enzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and ActivitiesChemistryCarbonic anhydraseEnzymeIsozymeSulfonamideGrowth inhibitionCell cultureBiochemistryIntracellularMechanism of action

MeSH terms

AnimalsAntineoplastic AgentsCarbonic AnhydrasesCarbonic Anhydrase InhibitorsCattleCell DivisionFemaleHumansIsoenzymesStructure-Activity RelationshipSulfonamidesTumor Cells, CulturedInhibitory Concentration 50

Funding

  • Centre National de la Recherche Scientifique
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Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents? · Scinovex