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Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

European Journal of Pharmacology · 1988 · Vol. 146(1) · pp. 185–186

Philip S. Portoghese✉Marjia Sultana(Twin Cities Orthopedics)A.E. Takemori(University of Minnesota)

Pain Mechanisms and Treatments Neuropeptides and Animal Physiology Pharmacological Receptor Mechanisms and EffectsNaltrindoleHyperalgesiaAgonistNociceptionDorsal root ganglionAnalgesicOpioidNociceptorPharmacologyChemistry

MeSH terms

AnimalsGuinea PigsIleumIndolesMaleMorphinansMuscle ContractionMuscle, Smooth, VascularNaltrexoneNarcotic AntagonistsReceptors, OpioidVas DeferensReceptors, Opioid, deltaMiceRats

Citations

613

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9.66

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99%

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Cited by

Opioids excite dopamine neurons by hyperpolarization of local interneurons

Journal of Neuroscience · 1992 · 1,621 citations

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