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Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients

Arthritis & Rheumatism · 2002 · Vol. 46(4) · pp. 1019–1027

Ricard Cervera✉(Consorci Institut D'Investigacions Biomediques August Pi I Sunyer)Jean‐Charles Piette(Sorbonne Université)Josep Font(Consorci Institut D'Investigacions Biomediques August Pi I Sunyer)Munther A. Khamashta(St Thomas' Hospital)Yehuda Shoenfeld(Sheba Medical Center)María Teresa Camps(Hospital Clínico San Carlos)Søren Jacobsen(Hvidovre Hospital)Gabriella Lakos(University of Debrecen)Anǵela Tincani(Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia)I. Kontopoulou‐Griva(Hippocration General Hospital)Mauro GaleazziPier Luigi Meroni(IRCCS Istituto Auxologico Italiano)Ronald H. W. M. Derksen(Utrecht University)Philip G. de Groot(Utrecht University)Erika Gromnica‐Ihle(Immanuel Krankenhaus)Marta Baleva(Medical University of Sofia)Marta Mosca(University of Pisa)Stefano Bombardieri(University of Pisa)Frédéric HoussiauJean‐Christophe Gris(Centre Hospitalier Universitaire de Nîmes)I. Quéré(Centre Hospitalier Universitaire de Nîmes)É. Hachulla(Hôpital Claude Huriez)Carlos Vasconcelos(Hospital de Santo António)Beate Roch(University Hospital Carl Gustav Carus)Antonio Fernández‐NebroMarie‐Claire Boffa(Sorbonne Université)Graham R.V. Hughes(St Thomas' Hospital)M Ingelmo(Consorci Institut D'Investigacions Biomediques August Pi I Sunyer)

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Abstract

APS may affect any organ of the body and display a broad spectrum of manifestations. An association with SLE, the patient's sex, and the patient's age at disease onset can modify the disease expression and define specific subsets of APS.

Systemic Lupus Erythematosus Research Rheumatoid Arthritis Research and Therapies Peripheral Neuropathies and DisordersLivedo reticularisMedicineAntiphospholipid syndromeCohortChoreaInternal medicineThrombosisStroke (engine)GastroenterologySurgery

MeSH terms

AdolescentAdultAgedAged, 80 and overAutoantibodiesChildChild, PreschoolDiagnosis, DifferentialFemaleHumansInfantInfant, NewbornMaleMiddle AgedCohort Studies

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2,137

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43.00

field-weighted impact

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100%

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