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TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes

Oncogene · 2007 · Vol. 26(15) · pp. 2157–2165
Audrey Petitjean✉Maria Isabel AchatzA.L. Børresen-DalePierre HainautMagali Olivier
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Cancer-related Molecular PathwaysCancer Genomics and DiagnosticsEpigenetics and DNA MethylationMissense mutationBiologyPhenotypeGeneticsCancerMutationTransactivationLoss functionBreast cancerAllele

MeSH terms

Genetic MarkersHumansMutationNeoplasmsPolymorphism, GeneticPrognosisBiomarkers, TumorTumor Suppressor Protein p53MutagenesisLi-Fraumeni Syndrome
Citations
888
FWCI
22.36
field-weighted impact
References
117
Percentile
100%
vs. same field & year
Citations per year
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References
p53, the Cellular Gatekeeper for Growth and Division
Cell · 1997 · 7,678 citations
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers
Oncogene · 2002 · 1,104 citations
p53 Mutations in Human Cancers
Science · 1991 · 8,098 citations
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Proceedings of the National Academy of Sciences · 2001 · 10,888 citations
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