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Expanded Adipose-Derived Stem Cells for the Treatment of Complex Perianal Fistula

Diseases of the Colon & Rectum · 2009 · Vol. 52(1) · pp. 79–86

Damián García‐Olmo✉(Universidad Autónoma de Madrid)Dolores HerrerosIsabel PascualJosé A. Pascual(Research Institute Hospital 12 de Octubre)Emilio Del-Valle(Hospital General Universitario Gregorio Marañón)Jaime Zorrilla(Hospital General Universitario Gregorio Marañón)Paloma De-La-QuintanaMariano García‐ArranzM. Pascual(Acerinox (Spain))

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Abstract

Administration of expanded ASCs (20 to 60 million cells) in combination with fibrin glue is an effective and safe treatment for complex perianal fistula and appears to achieve higher rates of healing than fibrin glue alone.

Anorectal Disease Treatments and Outcomes Colorectal Cancer Surgical Treatments Colorectal and Anal CarcinomasFibrin glueMedicineSurgeryFibrinWound healingFistulaAdipose tissueFibrin Tissue AdhesiveStem cellRandomized controlled trial

MeSH terms

AdultCrohn DiseaseFemaleHumansMaleMiddle AgedRectal FistulaTissue AdhesivesWound HealingFibrin Tissue AdhesiveAdipocytesMesenchymal Stem Cell Transplantation

Citations

773

FWCI

51.25

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

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