articleTop 1% cited
VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis
The American Journal of Gastroenterology · 2005 · Vol. 100(7) · pp. 1539–1546
Rodrigo Bibiloni(University of Alberta)Richard N. Fedorak✉(University of Alberta)Gerald W. TannockKaren Madsen(University of Alberta)Paolo Gionchetti(University of L'Aquila)Massimo Campieri(University of Bologna)Claudio De Simone(University of North Carolina at Chapel Hill)R. Balfour Sartor(University of North Carolina at Chapel Hill)
Abstract
Treatment of patients with mild to moderate UC, not responding to conventional therapy, with VSL#3 resulted in a combined induction of remission/response rate of 77% with no adverse events. At least some of the bacterial species incorporated in the probiotic product reached the target site in amounts that could be detected.
Inflammatory Bowel DiseaseGastrointestinal motility and disordersGut microbiota and healthMedicineUlcerative colitisProbioticGastroenterologyColitisInternal medicineBacteriaDisease
MeSH terms
AdultColitis, UlcerativeDNA, BacterialFemaleHumansMaleMiddle AgedRemission InductionTreatment OutcomeRetreatmentProbiotics
Citations
733
FWCI
31.26
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References
43
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100%
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References
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Alimentary Pharmacology & Therapeutics · 1999 · 564 citations
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Gut · 2003 · 911 citations
Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice
Infection and Immunity · 1998 · 1,472 citations
Probiotics
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