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Extracellular matrix: A dynamic microenvironment for stem cell niche

Biochimica et Biophysica Acta (BBA) - General Subjects · 2014 · Vol. 1840(8) · pp. 2506–2519
Francesca GattazzoAnna UrciuoloPaolo Bonaldo

Abstract

ECM is a key component of stem cell niches and is involved in various aspects of stem cell behavior, thus having a major impact on tissue homeostasis and regeneration under physiological and pathological conditions. This article is part of a Special Issue entitled Matrix-mediated cell behaviour and properties.

Tissue Engineering and Regenerative MedicineCancer Cells and MetastasisElectrospun Nanofibers in Biomedical ApplicationsStem cellExtracellular matrixCell biologyNicheBiologyStem cell nicheRegeneration (biology)Adult stem cellCellular differentiationCell type

MeSH terms

AnimalsExtracellular MatrixHumansCell LineageMechanotransduction, CellularStem Cell NicheBiophysical PhenomenaCellular Microenvironment

Funding

  • Università degli Studi di Padova
Citations
1,280
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