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Long-Term Outcome of 444 Patients with Distant Metastases from Papillary and Follicular Thyroid Carcinoma: Benefits and Limits of Radioiodine Therapy

The Journal of Clinical Endocrinology & Metabolism · 2006 · Vol. 91(8) · pp. 2892–2899

Cosimo Durante✉(Institut Gustave Roussy)Nadia Haddy(Inserm)E. Baudin(Institut Gustave Roussy)Sophie Leboulleux(Institut Gustave Roussy)Dana M. Hartl(Institut Gustave Roussy)J P Travagli(Institut Gustave Roussy)Bernard Caillou(Institut Gustave Roussy)M. Ricard(Institut Gustave Roussy)J. Lumbroso(Institut Gustave Roussy)Florent de Vathaire(Inserm)Martin Schlumberger(Institut Gustave Roussy)

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Abstract

(131)I treatment is highly effective in younger patients with (131)I uptake and with small metastases. They should be treated until the disappearance of any uptake or until a cumulative activity of 22 GBq has been administered. In the other patients, other treatment modalities should be used when tumor progression has been documented.

Thyroid Cancer Diagnosis and Treatment Radiopharmaceutical Chemistry and Applications Neuroendocrine Tumor Research AdvancesMedicineThyroid carcinomaThyroidLungCarcinomaFollicular phaseInternal medicineAdenocarcinomaHormoneNuclear medicine

MeSH terms

AdolescentAdultAgedBone NeoplasmsCarcinoma, PapillaryChildChild, PreschoolFemaleHumansIodine RadioisotopesLung NeoplasmsMaleMiddle AgedNeoplasm MetastasisPrognosis

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Guidelines for the management of thyroid cancer