article Open AccessTop 1% cited
Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis
Molecular Cell · 2007 · Vol. 26(5) · pp. 745–752
Tsung-Cheng Chang(Johns Hopkins University)Erik A. Wentzel(Johns Hopkins University)Oliver A. Kent(Johns Hopkins University)Kalyani Ramachandran(Johns Hopkins University)Michael E. Mullendore(Johns Hopkins University)Kwang Hyuck Lee(Johns Hopkins University)Georg Feldmann(Johns Hopkins University)Munekazu Yamakuchi(Johns Hopkins University)Marcella Ferlito(Johns Hopkins University)Charles J. Lowenstein(Johns Hopkins University)Dan E. Arking(Johns Hopkins University)M Beer(Johns Hopkins University)Anirban Maitra(Johns Hopkins University)Joshua T. Mendell✉(Johns Hopkins University)
MicroRNA in disease regulationCancer-related molecular mechanisms researchRNA modifications and cancerBiologymicroRNATransactivationReprogrammingCancer researchRegulation of gene expressionGeneCell biologyGene expressionDownregulation and upregulation
MeSH terms
Base SequenceDNA DamageHumansPancreatic NeoplasmsPromoter Regions, GeneticRNA, NeoplasmTranscriptional ActivationGene ExpressionTumor Suppressor Protein p53ApoptosisMicroRNAsCell Line, Tumor
Funding
- Rita Allen Foundation
- Lustgarten Foundation
- Allen Foundation
Citations
1,992
FWCI
52.66
field-weighted impact
References
62
Percentile
100%
vs. same field & year
Citations per year
Cited by
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
BMC Cancer · 2008 · 392 citations
miRNAs in human cancer
The Journal of Pathology · 2010 · 894 citations
The miR-34 family in cancer and apoptosis
Cell Death and Differentiation · 2009 · 1,232 citations
miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
Cancer Letters · 2008 · 429 citations
miR-29 miRNAs activate p53 by targeting p85α and CDC42
Nature Structural & Molecular Biology · 2008 · 604 citations
microRNAs Biogenesis, Functions and Role in Tumor Angiogenesis
Frontiers in Oncology · 2020 · 279 citations
Causes and consequences of microRNA dysregulation in cancer
Nature Reviews Genetics · 2009 · 3,006 citations
MicroRNAs: Novel regulators in the hallmarks of human cancer
Cancer Letters · 2009 · 446 citations
References
MicroRNAs
Cell · 2004 · 34,668 citations
Oncomirs — microRNAs with a role in cancer
Nature reviews. Cancer · 2006 · 7,016 citations
MicroRNA signatures in human cancers
Nature reviews. Cancer · 2006 · 7,589 citations
The functions of animal microRNAs
Nature · 2004 · 10,802 citations
Control of apoptosis by p53
Oncogene · 2003 · 1,397 citations
MicroRNAs: small RNAs with a big role in gene regulation
Nature Reviews Genetics · 2004 · 7,028 citations
A comparison of normalization methods for high densityoligonucleotide array data based on variance and bias
Bioinformatics · 2003 · 8,399 citations
DAVID: Database for Annotation, Visualization, and Integrated Discovery
Genome biology · 2003 · 9,433 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.