review Open AccessTop 1% cited

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

Acta Neuropathologica · 2009 · Vol. 118(1) · pp. 103–113

Robert D. Bell✉Berislav V. Zloković(University of Rochester)

Alzheimer's disease research and treatments Intracerebral and Subarachnoid Hemorrhage Research Neurological Disease Mechanisms and TreatmentsCerebral amyloid angiopathyCerebral blood flowBlood–brain barrierMedicinePathologyNeuroscienceCognitive declineDementiaCerebral circulationStroke (engine)

MeSH terms

MyocardinAlzheimer DiseaseAnimalsApolipoproteins EBlood-Brain BarrierBrainCerebrovascular CirculationCerebrovascular DisordersHumansMacrophagesNuclear ProteinsTrans-ActivatorsAmyloid beta-PeptidesCerebral Amyloid AngiopathyReactive Oxygen Species

Funding

Chinese Academy of Agricultural Sciences
National Institutes of Health

Citations

854

FWCI

32.73

field-weighted impact

References

103

Percentile

100%

vs. same field & year

Citations per year

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References

Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid

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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

Neuron · 2008 · 3,202 citations

Lymphatic drainage of the brain and the pathophysiology of neurological disease

Acta Neuropathologica · 2008 · 486 citations

Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat

Journal of Cerebral Blood Flow & Metabolism · 2006 · 1,044 citations

Pericytes and vascular stability

Experimental Cell Research · 2005 · 501 citations

Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous System

Journal of Cerebral Blood Flow & Metabolism · 2006 · 667 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Science · 1993 · 9,373 citations

Neurovascular regulation in the normal brain and in Alzheimer's disease

Nature reviews. Neuroscience · 2004 · 2,187 citations

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