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How much loss to follow-up is acceptable in long-term randomised trials and prospective studies?

Archives of Disease in Childhood · 2008 · Vol. 93(6) · pp. 458–461
Mary FewtrellKathy KennedyAmit SinghalRichard M. MartinAndy NessMijna Hadders‐AlgraBerthold KoletzkoAlan Lucas

Abstract

to test early nutritional interventions and prospective observational cohorts. RCTs are generally accepted as methodologically the best approach for informing health policy. They can equalise unknown as well as known confounding factors and so can demonstrate causation; they permit estimation of effect size and so can be used to assess likely economic

Diet and metabolism studiesBirth, Development, and HealthNutrition and Health in AgingMedicineTerm (time)Prospective cohort studyMEDLINEIntensive care medicinePediatricsSurgery

MeSH terms

AdolescentAdultChildDevelopmental DisabilitiesChild, PreschoolData Interpretation, StatisticalFemaleFollow-Up StudiesHumansInfantInfant, NewbornMalePatient DropoutsPregnancyProspective Studies
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How much loss to follow-up is acceptable in long-term randomised trials and prospective studies? · Scinovex