article Open AccessTop 1% cited
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Nature Structural & Molecular Biology · 2015 · Vol. 22(5) · pp. 362–369
Wesley K. Kroeze✉(University of North Carolina at Chapel Hill)Maria F. Sassano(University of North Carolina at Chapel Hill)Xi‐Ping Huang(University of North Carolina at Chapel Hill)Katherine Lansu(University of North Carolina at Chapel Hill)John D. McCorvy(University of North Carolina at Chapel Hill)Philippe Giguère(University of North Carolina at Chapel Hill)Noah Sciaky(University of North Carolina at Chapel Hill)Bryan L. Roth(National Institute of Mental Health)
Receptor Mechanisms and SignalingMass Spectrometry Techniques and ApplicationsNeuropeptides and Animal PhysiologyDruggabilityG protein-coupled receptorInterrogationComputational biologyDrug discoveryBiologySignal transductionBioinformaticsCell biologyGenetics
MeSH terms
beta-ArrestinsAmino Acid SequenceBiological AssayHumansLigandsTranscription, GeneticTranscriptional ActivationArrestinsRNA InterferenceRNA, Small InterferingReceptors, G-Protein-Coupled
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The Repertoire of G-Protein–Coupled Receptors in Fully Sequenced Genomes
Molecular Pharmacology · 2005 · 624 citations
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
Genomics · 2006 · 456 citations
The druggable genome
Nature Reviews Drug Discovery · 2002 · 3,271 citations
TGF-β SIGNAL TRANSDUCTION
Annual Review of Biochemistry · 1998 · 7,560 citations
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