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Gender Differences in Human Sepsis

Archives of Surgery · 1998 · Vol. 133(11) · pp. 1200–1200
Jörg Schröder

Abstract

In this prospective study, gender differences were confirmed in human sepsis, with a significantly better prognosis for women, which may be related to increased levels of anti-inflammatory mediators. The hypothetical different ratio of proinflammatory and anti-inflammatory mediators may be important for further therapeutic interventions in sepsis.

Sepsis Diagnosis and TreatmentAdrenal Hormones and DisordersThermal Regulation in MedicineMedicineSepsisProinflammatory cytokineProspective cohort studyHormoneInternal medicineGastroenterologyIntensive care unitOrgan dysfunctionInflammation

MeSH terms

EstradiolFemaleHumansMaleMiddle AgedMultiple Organ FailurePostoperative ComplicationsPrognosisProspective StudiesSex CharacteristicsTestosteroneTumor Necrosis Factor-alphaInterleukin-6Survival AnalysisInterleukin-10
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References
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The Journal of Immunology · 1991 · 2,896 citations
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