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Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study
Critical Care · 2007 · Vol. 11(6) · pp. R127–R127
Catherine L. Dent✉(Cincinnati Children's Hospital Medical Center)Qing Ma(Cincinnati Children's Hospital Medical Center)Sudha Dastrala(University of Cincinnati)Michael Bennett(Cincinnati Children's Hospital Medical Center)Mark Mitsnefes(Cincinnati Children's Hospital Medical Center)Jonathan Barasch(Columbia University)Prasad Devarajan(University of Cincinnati)
Abstract
Accurate measurements of plasma NGAL are obtained using the point-of-care Triage(R) NGAL device. Plasma NGAL is an early predictive biomarker of AKI, morbidity, and mortality after pediatric CPB.
Acute Kidney Injury ResearchTrauma, Hemostasis, Coagulopathy, ResuscitationCardiac, Anesthesia and Surgical OutcomesMedicineNeutrophil gelatinase-associated lipocalinAcute kidney injuryProspective cohort studyCardiac surgeryLipocalinIntensive care medicineCohortCohort studyInternal medicine
MeSH terms
Lipocalin-2Acute-Phase ProteinsChildChild, PreschoolCross-Sectional StudiesFemaleCardiac Surgical ProceduresHumansMaleMorbidityMortalityPilot ProjectsPredictive Value of TestsProspective StudiesProto-Oncogene Proteins
Funding
- American Heart Association
- Cincinnati Children's Hospital Medical Center
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases
Citations
481
FWCI
15.87
field-weighted impact
References
33
Percentile
100%
vs. same field & year
Citations per year
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References
Independent Association between Acute Renal Failure and Mortality following Cardiac Surgery
The American Journal of Medicine · 1998 · 1,174 citations
Dual Action of Neutrophil Gelatinase–Associated Lipocalin
Journal of the American Society of Nephrology · 2007 · 773 citations
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Journal of the American Society of Nephrology · 2004 · 1,335 citations
Identification of Neutrophil Gelatinase-Associated Lipocalin as a Novel Early Urinary Biomarker for Ischemic Renal Injury
Journal of the American Society of Nephrology · 2003 · 1,732 citations
Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group
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