articleTop 10% cited

FR901228, a Potent Antitumor Antibiotic, Is a Novel Histone Deacetylase Inhibitor

Experimental Cell Research · 1998 · Vol. 241(1) · pp. 126–133

Hidenori Nakajima(Fujisawa City Hospital)Young Bae Kim(The University of Tokyo)Hiroshi TeranoMinoru Yoshida✉(The University of Tokyo)Sueharu Horinouchi(The University of Tokyo)

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Histone Deacetylase Inhibitors Research Signaling Pathways in Disease Synthetic Organic Chemistry MethodsTrichostatin AHistone deacetylase inhibitorHistone deacetylaseBiologyHistone deacetylase 5ChromatinHDAC11Histone deacetylase 2HDAC10Acetylation

MeSH terms

AcetylationAnti-Bacterial AgentsAntibiotics, AntineoplasticCell DivisionEnzyme InhibitorsHistonesHumansHydroxamic AcidsPeptides, CyclicPromoter Regions, GeneticSimian virus 40Transcription, GeneticTumor Cells, CulturedTranscriptional ActivationDepsipeptides

Citations

487

FWCI

8.16

field-weighted impact

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98%

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Cited by

Histone Deacetylase Inhibitors: Inducers of Differentiation or Apoptosis of Transformed Cells

JNCI Journal of the National Cancer Institute · 2000 · 1,162 citations

References

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Journal of Immunological Methods · 1983 · 55,054 citations

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