articleTop 10% cited
Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
Leukemia · 1998 · Vol. 12(9) · pp. 1333–1337
Hitoshi Kiyoi✉(Nagoya University)Masayuki Towatari(Nagoya University)Shohei Yokota(Kyoto Prefectural University of Medicine)Motohiro Hamaguchi(Nagoya University)R Ohno(Hamamatsu University School of Medicine)Hidehiko Saito(Nagoya University)T Naoe(Nagoya University)
Acute Myeloid Leukemia ResearchCancer Genomics and DiagnosticsProtein Degradation and InhibitorsBiologyGene duplicationMutantMutationGeneTandem exon duplicationGeneticsPhosphorylationMolecular biology
MeSH terms
Proto-Oncogene ProteinsAcute DiseaseAnimalsChromosome MappingHumansLeukemia, MyeloidMutationMyelodysplastic SyndromesNeoplasm ProteinsPhosphorylationSequence AnalysisReceptors, Platelet-Derived Growth FactorCOS CellsReceptor Protein-Tyrosine Kinasesfms-Like Tyrosine Kinase 3
Funding
- Uehara Memorial Foundation
- Kanae Foundation for the Promotion of Medical Science
Citations
448
FWCI
4.34
field-weighted impact
References
0
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95%
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Citations per year
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Identification of novel <i>FLT‐3</i> Asp835 mutations in adult acute myeloid leukaemia
British Journal of Haematology · 2001 · 379 citations
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