review Open Access

The regulation of E2F by pRB-family proteins

Genes & Development · 1998 · Vol. 12(15) · pp. 2245–2262

Nicholas J. Dyson✉(Massachusetts General Hospital)

Cancer-related Molecular Pathways RNA modifications and cancer Cancer-related gene regulationBiologyE2FCell biologyGeneticsRetinoblastoma proteinDNA-binding proteinComputational biologyTranscription factorGeneCell cycle

MeSH terms

AnimalsBinding SitesCarrier ProteinsDNA-Binding ProteinsHumansOncogenesPhosphorylationRepressor ProteinsTranscription FactorsTranscriptional ActivationGenes, Tumor SuppressorRetinoblastoma ProteinS PhaseApoptosisCell Cycle Proteins

Funding

National Institutes of Health

Citations

2,307

FWCI

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field-weighted impact

References

227

Percentile

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vs. same field & year

Citations per year

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References

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G<sub>1</sub>/S-Regulatory Genes

Molecular and Cellular Biology · 1995 · 910 citations

A Kinematic Notation for Lower-Pair Mechanisms Based on Matrices

Journal of Applied Mechanics · 1955 · 4,447 citations

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