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Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia

Arthritis & Rheumatism · 2002 · Vol. 46(5) · pp. 1333–1343
Richard H. GracelyFrank PetzkeJulie M. WolfDaniel J. Clauw

Abstract

The fact that comparable subjectively painful conditions resulted in activation patterns that were similar in patients and controls, whereas similar pressures resulted in no common regions of activation and greater effects in patients, supports the hypothesis that FM is characterized by cortical or subcortical augmentation of pain processing.

Fibromyalgia and Chronic Fatigue Syndrome ResearchMusculoskeletal pain and rehabilitationPain Management and Placebo EffectFibromyalgiaFunctional magnetic resonance imagingMagnetic resonance imagingStimulationStimulus (psychology)MedicineBlood pressureAnesthesiaCerebral blood flowInternal medicine

MeSH terms

AdultAgedBrainFemaleFibromyalgiaHumansMagnetic Resonance ImagingMaleMiddle AgedPainPsychophysicsPain Threshold
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References
A Three-Dimensional Statistical Analysis for CBF Activation Studies in Human Brain
Journal of Cerebral Blood Flow & Metabolism · 1992 · 2,053 citations
Automated Talairach Atlas labels for functional brain mapping
Human Brain Mapping · 2000 · 3,421 citations
Co-Planar Stereotaxic Atlas of the Human Brain
Medical Entomology and Zoology · 1988 · 11,679 citations
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