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Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure
Journal of Hypertension · 2002 · Vol. 20(11) · pp. 2183–2189
Takayoshi Ohkubo✉(Faculty of Public Health)Atsushi Hozawa(Faculty of Public Health)Junko Yamaguchi(Therapeutics Clinical Research)Masahiro Kikuya(Therapeutics Clinical Research)Kaori Ohmori(Faculty of Public Health)Mari Michimata(Therapeutics Clinical Research)Mitsunobu Matsubara(Therapeutics Clinical Research)Junichiro Hashimoto(Therapeutics Clinical Research)Haruhisa Hoshi(Miwa Hospital)Tsutomu Araki(Therapeutics Clinical Research)Ichiro Tsuji(Faculty of Public Health)Hiroshi Satoh(Tohoku University)Shigeru Hisamichi(Faculty of Public Health)Yutaka Imai(Therapeutics Clinical Research)
Abstract
This is the first study to demonstrate that a diminished nocturnal decline in blood pressure is a risk factor for cardiovascular mortality, independent of the overall blood pressure load during a 24-h period, in the general population.
Blood Pressure and Hypertension StudiesHeart Rate Variability and Autonomic ControlCardiovascular Syncope and Autonomic DisordersBlood pressureMedicineAmbulatory blood pressureNocturnalCardiologyPopulationInternal medicineConfoundingRisk factorDiastole
MeSH terms
AgedBlood PressureBlood Pressure DeterminationCircadian RhythmFemaleFollow-Up StudiesHumansHypertensionMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk Factors
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References
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